Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization ...

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The ...

Two novel agents targeting angiopoietin-like protein 3 demonstrated safety and lipid-lowering capabilities in phase 2 trials, ...

Integral membrane proteins carry out essential functions in the cell, and their activities are often modulated by specific protein-lipid interactions in the ... (b) topology diagram of glpg indicating ...

Department of Bioengineering Technologies, Leijten Laboratory, Faculty of Science and Technology, Technical Medical Centre, University of Twente, Drienerlolaan 5, Enschede 7522NB, The Netherlands ...

Most often, the building block of oligomeric and aggregated species is the protein’s unfolded/misfolded/partially folded monomer. The structure of such aggregates highly depends on the conformation of ...

unreplicated chromosome is given by For the purposes of this model, we neglect to include the difference in the leading-versus lagging-strands, and model the fork itself as a standard DNA monomer. We ...