In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A ...

Led by Maurizio Pellecchia, a professor of biomedical sciences in the UCR School of Medicine, the team found that the degraders, which were made in the lab, act like "molecular crowbars" that open up ...

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The chemistry of photography is based on photosensitivity and reactions with light. The chemical processes that create a traditional photograph start inside the camera with the absorption of photons.

But no one knew whether they might work as a team to enter an egg, or how. In the new study, Andrea Pauli, a molecular and developmental biologist at the Research Institute of Molecular Pathology ...

We used a two-step extraction process to isolate as diverse chemical mixtures as possible," says Georg Braun, postdoctoral researcher in Beate Escher's working group and first author of the study.

Capital structure describes the mix of a firm's long-term capital—a mix of debt and equity—that it uses to fund its ongoing operations and future growth. A company's capital structure is ...

Herein, Ivic et al. studied the effects of long-term treatment with metformin and liraglutide in elderly male and female rats fed a high-fat high-sugar. Even though, metformin treatment appears to be ...

Big Pharma is sticking to the recent molecular glue investment trend, with Pfizer now the latest major drugmaker to get in on the action. Pfizer is laying out $49 million upfront in a partnership ...

During the invalidation, CNIPA rejected all claims for lack of inventive step in view of liraglutide, a molecule with a similar structure and mechanism of action. Novo Nordisk responded by arguing ...