eLife3d
Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in obesity
Department of Physiology, Harold Hamm Diabetes Center, The University of Oklahoma Health Science Center, Oklahoma City, United States ...
The EMBO Journal4d
Circadian rhythms of macrophages are altered by the acidic tumor microenvironment
Tumor-associated macrophages (TAMs) are prime therapeutic targets due to their pro-tumorigenic functions, but varying efficacy of macrophage-targeting therapies highlights our incomplete understanding ...
Frontiers6d
GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma
We aimed to investigate the influence of sex disparities on the proliferation and accumulation of macrophages, one of the major components of the tumor microenvironment, in hepatocellular carcinoma ...
Medscape1d
Mediators of inflammation
A GP130-Targeting Small Molecule, LMT-28, Reduces LPS-Induced Bone Resorption around Implants in Diabetic Models by Inhibiting IL-6/GP130/JAK2/STAT3 Signaling.
verywellhealth6d
What 'Alert and Oriented' Means With Dementia
The term "alert and oriented" (AO) is a medical notation describing a person's level of consciousness and cognition (the ability to understand and learn through thought, experiences, and the senses).