Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion.

BP1 is a key player in DNA repair and together with BRCA1 regulate selection of DNA double strand break repair mechanisms. Localization of DNA repair factors to sites of DNA damage by 53BP1 is ...

The method, called KMAP, enables intuitive visualisation of short DNA sequences ... RNA-binding proteins and their binding preferences. Its ability to reveal structure in complex sequence data makes ...

UC San Diego researchers reveal PHGDH as a causal gene in Alzheimer's, linking its regulatory role to disease progression and ...

The achievement represents a major step forward, potentially unlocking innovations across numerous fields that rely on ...

A scientific revolution is underway as researchers push to bring atomic-level precision, once reserved for small molecule ...

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

Researchers have discovered that a gene previously seen as a biomarker for Alzheimer’s disease, PHGDH, actually plays a causal role by disrupting gene regulation in the brain.

The RNA cloud formed around genes regulates their readout into RNA. Triplexes help define where in the genome a cloud forms. Proteins and other flipons modulate the levels of gene expression. The ...

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

A new study reveals that the way DNA folds inside brain cells plays a critical role in glioblastoma, one of the deadliest forms of brain cancer.

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer called glioblastoma, suggests a new preclinical study from Weill Cornell ...