Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

The San Francisco 49ers have reportedly emerged as a strong candidate to sign free-agent quarterback Daniel Jones. According ...

San Francisco 49ers offensive tackle Trent Williams was seen in the locker room on Wednesday using a scooter as he recovers ...

Amid a wicked Super Bowl hangover and heading towards what is likely a losing season, it’s natural that head coach Kyle ...

One of the top receivers in the league will be featured when George Kittle and the San Francisco 49ers visit the Buffalo ...

For the team's annual "Feast with the Niners" presented by Graton Casino event, the 49ers hosted low-income and transitional ...

The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's ...

Following their bye week, the Bills (9-2) will take on the San Francisco 49ers (5-6) at Highmark Stadium in Week 13. But ...

No Brock Purdy or Nick Bosa, but the 49ers are optimistic Trent Williams can now play, he’ll be evaluated pre-game.

A local 14-year-old middle school student thought he won a football signed by the reigning NFL Offensive Player of the Year — ...

With Daniel Jones’ time coming to an end with the New York Giants earlier this week, the NFL world wanted to know about his ...