Now, for the first time, a retrotransposon has been caught in action inside a cell: Refining cryo-Electron Tomography (cryo-ET) techniques, scientists imaged the retrotransposon copia in the egg ...
Modern mammalian genomes, for example, are riddled with the scars of these copy-and-paste events, with retrotransposon-derived DNA now accounting for nearly 50 percent of the human genome. The most ...
Researchers have known that retrotransposon insertion in the centromere has contributed to this variation and rapid evolution ...
For the first time, scientists have visualized a retrotransposon, a “jumping gene”, inside the cell of a complex organism. Advanced cryo-Electron Tomography allowed this feat at sub-nanometer ...
Inflammasomes are huge, multi-protein complexes inside cells that spark inflammation when they sense danger. Inflammasomes can also sound the alarm when no pathogens are present, contributing to ...
We propose that silencing of retrotransposons occurs by cosuppression during early embryogenesis, but that this process is imperfect and produces a mosaic pattern of retrotransposon expression in ...
Following translation, reverse transcriptase converts the retrotransposon RNA into double-stranded DNA. This DNA copy of the retrotransposon then integrates, at a new location, into the genome of ...
We have carried out pioneering work on the development and application of retrotransposon markers in barley, in an EU project with the major European groups who are developing them for other crops.