Fernando Tatís Jr., Manny Machado and Donovan Solano gifted the San Diego Padres with plenty of insurance against the Houston ...

The Chicago Cubs breakout prospect has a brother also trying to make it into the big leagues with the San Diego Padres.

The Houston Astros (82-69) and San Diego Padres (86-66) meet Wednesday for the finale of a 3-game series. First pitch from ...

Astros starter Framber Valdez made one mistake in seven innings, and it ended up handing him a tough-luck loss as he was ...

The San Diego Padres will go for two in a row in the series when they welcome the Houston Astros to Petco Park on Tuesday ...

Manny Machado hit a solo home run that gave the San Diego Padres a 1-0 lead over the Houston Astros.

Luis Arraez has now gone 135 consecutive plate appearances without recording a single strikeout, placing the Padres All-Star ...

The Astros' four-game winning streak ended and Houston's American League West lead was cut to four games with a loss to the ...

In the second game of a three-game series at Oracle Park, the San Francisco Giants (72-76) play the San Diego Padres (83-65), ...

Analyzing Friday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

In an electrifying showdown, the San Diego Padres clinched a resounding 4-0 victory over the Houston Astros, captivating fans ...

You can see player prop bet odds for Jurickson Profar, Andrew Vaughn and others on the San Diego Padres and Chicago White Sox ...