C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic ...

The researchers found that the zinc finger proteins ZNF512 and ZNF512B are localized at the pericentric heterochromatin regions by their specific binding to pericentric heterochromatin DNA.

in Sp1-DNA binding. Sp1 is a protein that has multiple zinc-finger motifs, or regions known to bind to zinc; however, the inclusion of EDTA, an agent that chelates metal ions, inhibits zinc binding.

as DNA recognition and cutting take place in one protein segment. Another result of this research are zinc finger nucleases. These artificial enzymes consist of a sub-unit that recognizes the desired ...